The telomere effect A revolutionary approach to living younger, healthier, longer

Telomeres can be thought of as biological aglets (the plastic tubes at the ends of shoelaces that keep them from getting ragged). They are repeating bits of noncoding DNA at the ends of chromosomes that prevent genetic stuff from coming undone. Nobel Prize-winning molecular biologist Blackburn and psychologist Epel report on the science and nature of telomeres, especially their size. Genetics and lifestyle affect telomere length. Telomeres truncate every time a cell divides. Short telomeres are associated with early onset of some chronic diseases and hastier death. Certain chemicals, cigarette smoking, and depression are related to shortened telomeres, while other toxins are linked to longer ones. The lengthening of telomeres slows aging. Cardiovascular exercise, quality sleep, and good mental health also can elongate telomeres. A revitalizing enzyme produced by the body, telomerase, also promotes the integrity of telomeres. Be warned that drawn-out telomeres are associated with genetic mutations and cancers. The optimal telomere resembles an object of Goldilocks' finickiness, definitely not too short but probably not too long. A fascinating look at yet another marvel of the human body.--Miksanek, Tony Copyright 2017 Booklist

Telomeres are the caps at the end of each strand of DNA that protect our chromosomes and their genetic materials and allow for the division and renewal of cells. Over time, all telomeres weaken, but some people have prematurely deteriorating telomeres, which inhibit cell renewal and lead to early aging and health issues. Blackburn (biology and physiology) and Epel (psychiatry, both Univ. of California, San Francisco) argue that one can change the decaying of our telomeres by changing our diet, exercise, environment, and mental habits. The audiobook includes PDF files with supplemental materials to help listeners determine if they may be at risk of premature aging. Reader Suzanne Toren clearly and carefully presents this complicated material. VERDICT Part scientific study, part self-help book, this work will interest listeners concerned about wellness and aging. A cutting-edge addition to any library's health and science section.--Stephen L. Hupp, West Virginia Univ. Parkersburg Lib. © Copyright 2017. Library Journals LLC, a wholly owned subsidiary of Media Source, Inc. No redistribution permitted.