An exercise in uncertainty A memoir of illness and hope

Jonathan Gluck

Book - 2025

"At age thirty-eight, Jonathan Gluck, a new father with a promising journalism career, was shocked to learn he had multiple myeloma, a rare, incurable blood cancer. He was told he had eighteen months to live. That was more than twenty years ago. Gluck isn't just something of a medical miracle. He's also part of a growing population. Thanks to revolutionary medical advances, many cancers and other serious illnesses are no longer death sentences, but chronic diseases people can often live with for years. While doctors continue to look for "magic-bullet" cures, they can now extend patients' lives by slowing the progression of their diseases one treatment at a time. The result is a strange, new no-man's land b...etween being sick and being well where Gluck and millions of others reside. In An Exercise in Uncertainty, Gluck maps this previously uncharted territory. Among the many vexing side effects of chronic illness he explores is uncertainty-never knowing from one day to the next how one's illness might change them physically, emotionally, spiritually. When you have an incurable disease, how do you cope with knowing that even when you're in remission, it will eventually return? How do you live with the anxiety, the fear, the near-constant awareness of your mortality? For Gluck, one surprising answer is fly fishing. If you're looking for peace in your own sea of uncertainty, it might be something else. As Gluck will be the first to say, cancer has absolutely nothing good to offer, but almost dying has taught him valuable lessons about how to live"-- Provided by publisher.

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Subjects
Genres
Autobiography
Biography
Informational works
Autobiographies
Biographies
Documents d'information
Published
New York, NY : Harmony [2025]
Language
English
Main Author
Jonathan Gluck (author)
Edition
First edition
Physical Description
286 pages ; 22 cm
Bibliography
Includes bibliographical references.
ISBN
9780593735787
  • Author's Note
  • Part 1. The Slip
  • Part 2. Diagnosis
  • Part 3. Limbo
  • Part 4. Recurrence
  • Part 5. RVD
  • Part 6. Clinical Trial
  • Part 7. Immunotherapy
  • Part 8. CAR-T
  • Part 9. Reflection
  • Acknowledgments
  • Notes
Review by Booklist Review

It seemed innocuous at the time. Healthy, 37 years old, journalist Gluck slipped on some ice and twisted his hip in 2002. About a year later, lingering pain prompted his visit to a doctor, and an MRI scan revealed a tumor. The diagnosis was multiple myeloma, a relatively rare cancer from malignant plasma cells in bone marrow. Gluck chronicles his transformation into a "cancer zombie," a person "permanently half sick and half well." His treatments included targeted radiation therapy, chemotherapy, and immunotherapy. "Because cancer is a nuclear bomb, not a conventional weapon, the fallout is widespread," Gluck writes. Adverse effects both physical and emotional arise from the myeloma and its treatment. He eloquently communicates his fear, self-pity, "catastrophizing," frustrating hassles with medical insurance, and chronic sense of uncertainty because of his condition. He also embraces the love, joy, and sense of accomplishment associated with his two children, his professional writing career, and the sport of fly-fishing. As a cancer survivor, Gluck believes he is still alive "because of science," but he emphasizes the immeasurable value of hope.

From Booklist, Copyright (c) American Library Association. Used with permission.
Review by Publisher's Weekly Review

Former New York magazine deputy editor Gluck highlights his experiences as a cancer survivor in this touching debut. In 2003, a 38-year-old Gluck learned he had multiple myeloma, a "rare and incurable bone marrow malignancy," and was told he had at most three years to live. (Doctors only detected the disease because Gluck asked for an MRI after slipping on ice outside of his office.) A new father, Gluck suddenly found his days revolving around Kafkaesque attempts to navigate health insurance and to schedule tests. All the while, he continued to beat the odds, and he credits the fact that he's still alive today to his early detection of the myeloma. Gluck offers sharp reflections about the taxing uncertainty of life in remission, candidly recounting fights with his wife about her stoicism ("What kind of person doesn't dissolve into a puddle of tears or break down when their spouse is diagnosed with cancer?") and acknowledging that, given his cancer's incurability, he "feels as though I'm locked in a basement that's slowly filling with water." His love of fly-fishing (it "may not be my church or my therapy, but I began to use it for similar purposes") offers welcome levity. Readers grappling with difficult diagnoses--for themselves or their loved ones--will find Gluck's perspective refreshing. Agent: Daniel Greenberg, Levine Greenberg Rostan. (June)

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