Replaceable you Adventures in human anatomy

Mary Roach

Book - 2025

"The body is the most complex machine in the world, and the only one for which you cannot get a replacement part from the manufacturer. For centuries, medicine has reached for what's available--sculpting noses from brass, borrowing skin from frogs and hearts from pigs, crafting eye parts from jet canopies and breasts from petroleum by-products. Today we're attempting to grow body parts from scratch using stem cells and 3D printers. How are we doing? Are we there yet? In Replaceable You, Mary Roach explores the remarkable advances and difficult questions prompted by the human body's failings. When and how does a person decide they'd be better off with a prosthetic than their existing limb? Can a donated heart be made... to beat forever? Can an intestine provide a workable substitute for a vagina? Roach dives in with her characteristic verve and infectious wit. Her travels take her to the OR at a legendary burn unit in Boston, a "superclean" xeno-pigsty in China, and a stem cell "hair nursery" in the San Diego tech hub. She talks with researchers and surgeons, amputees and ostomates, printers of kidneys and designers of wearable organs. She spends time in a working iron lung from the 1950s, stays up all night with recovery techs as they disassemble and reassemble a tissue donor, and travels across Mongolia with the cataract surgeons of Orbis International. Irrepressible and accessible, Replaceable You immerses readers in the wondrous, improbable, and surreal quest to build a new you"--

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Subjects
Genres
Informational works
Published
New York, NY : W.W. Norton & Company [2025]
Language
English
Main Author
Mary Roach (author)
Edition
First edition
Physical Description
276 pages : illustrations ; 22 cm
Bibliography
Includes bibliographical references (pages 264-276).
ISBN
9781324050629
  • First Thoughts
  • 1. To Build a Nose The Dawn of Replacement Body Parts
  • 2. Gimme Some Skin Replacing the Human Exterior
  • 3. Mixed Meats Humans with Pig Organs, and Pigs with Human Organs
  • 4. Heart in a Box Creating Ultra-Long-Life Organs
  • 5. The Vagina Dialogue Repurposing Your Parts
  • 6. Giving the Finger Some Transplants Are Tougher Than Others
  • 7. The Cut-Off Point Longing for a Prosthetic Leg
  • 8. Joint Ventures Woodworking Without Wood
  • 9. Intubation for Dummies The Brief Terrors of Mechanical Breathing
  • 10. Heavy Breathing Inside the Iron Lung
  • 11. The Mongolian Eyeball With Cataract Surgery, Sometimes Simpler Is Better
  • 12. The Last Six Inches Battling the Stigma of Ostomy
  • 13. Out of Ink How to Print a Human
  • 14. Shaft Hair Transplants Through the Ages
  • 15. Splitting Hairs Grow Yourself from Scratch!
  • 16. The Ass Men Chasing Perfection with Math and Fat
  • 17. Some of the Parts A Day in the Life of a Tissue Donor
  • Last Thoughts
  • Epilogue
  • Acknowledgments
  • Sources
Review by Kirkus Book Review

A lively treatise on the human body as an endlessly interchangeable set of parts. It's an old saw (and, these days, canard) that British teeth are bad. All the same, Roach, an indefatigable researcher, turns up a gem at the start of her latest book: Paul McCartney's father once suggested that Paul "have all my teeth taken out and false teeth put in," since he'd likely lose his original set soon enough. Her catalog of cut-and-paste body parts goes on, corporeal trivia mixed with solid, elegantly written scientific journalism. One such part is the nose, none too easy to craft a replacement for, as witness the eminent Danish astronomer Tycho Brahe, who lost his original proboscis in a duel. "Occasionally," Roach quotes one biographer as saying of its substitute, "it would drop off." Other appendages await, not least the male member. Given that cataract surgery is now almost assembly-line common, Roach wonders, what about elective surgeries to replace underperforming parts? No, not that part; rather, Roach tells the story of a former Marine who had suffered an injury that led to his toes dragging and thus arranged (by shooting himself in the afflicted foot) for an amputation and refitting with a prosthetic that allowed him to walk more easily. Roach wanders through the hallways of eldritch laboratories where pigs are grown to provide organs that are transplantable to humans, and she visits cadaver labs to look at another source of carefully inventoried parts ("As much time is spent on documentation and shipping of a donor's tissues as on their removal. You're expectingThe Jeffrey Dahmer Story but it's closer to UPS"). She interviews researchers on cures for type 1 diabetes and advances in "in vitro gametogenesis" and generally has a grand time looking into areas where few writers--especially squeamish ones--have ventured. An amiably entertaining, endlessly intriguing stroll through the stuff of which we're made. Copyright (c) Kirkus Reviews, used with permission.

Copyright (c) Kirkus Reviews, used with permission.