V is for Venom Agatha Christie's chemicals of death

Kathryn Harkup

Book - 2025

Fourteen stories. Fourteen more poisons. Just because it's fiction doesn't mean it's all made-up ... Agatha Christie is renowned for her captivating plots and creative ways of killing off ill-fated victims. And what better way to add intrigue to a story than poison? The surreptitious ways they can be administered and the characteristic symptoms they produce make these killer chemicals the ideal method of murder in a 'whodunit'. Christie perfected the use of poisons in her plots; her deft and varied use of toxic substances is one of her great strengths as a writer. But how is it that some compounds prove so fatal, and in such tiny amounts? The follow up to Kathryn Harkup's best-selling A is for Arsenic, V is for... Venom is a compelling exploration of Christie's use of poisons and her extensive chemical knowledge. Featuring fourteen more poisons from the works of Agatha Christie, this book investigates the science behind the deadly substances, the history of their use in real-life murder cases, and how feasible was it to obtain, administer and detect these poisons in Christie's time and today. Combining Christie's murder mysteries, chemical science and true crime, V is for Venom is a celebration of the use of science by the undisputed Queen of Crime.

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Subjects
Genres
Literary criticism
Published
London : Bloomsbury Sigma 2025.
Language
English
Main Author
Kathryn Harkup (author)
Physical Description
320 pages : illustrations ; 22 cm
Bibliography
Includes bibliographical references (pages 312-313) and index.
ISBN
9781399413077
  • The Queen of Crime
  • A is for Arrow Poison - 'The Case of the Caretaker' (Miss Marple's Final Cases)
  • B is for Bacteria - Cards on the Table
  • C is for Caimo - The Mirror Crack'd from Side to Side
  • F is for Formic Acid - 'The Lemesurier Inheritance' (Poirot's Early Cases)
  • G is for Gas - A Caribbean Mystery
  • H is for Hydrochloric Acid - Murder in Mesopotamia
  • J is for Jasmine - The Big Four
  • M is for Mickey Finn - Passenger to Frankfurt
  • N is for Nitroglycerin - 'The Chocolate Box' (Poirot's Early Cases)
  • O is for Oxalic Acid - Murder is Easy
  • P is for Procaine - One.Two, Buckle My Shoe
  • S is for Scopolamine - 'Philomel Cottage' (The Listerdale Mystery)
  • T is for Taxine - A Pocket Full of Rye
  • V is for Venom - Death in the Clouds
  • Appendix: Christie's Causes of Death
  • Selected Bibliography
  • Acknowledgements
  • Index
Review by Booklist Review

Agatha Christie had a wonderful way with plots and poisons, according to Harkup, a former chemist and author of A Is for Arsenic: The Poisons of Agatha Christie (2015), which was both shortlisted for a Mystery Readers International Macavity Award and recognized for its outstanding contribution to medical literature by the British Medical Association. This follow-up presents fourteen more letters in the toxicology ABCs, and the Christie tales that showcased the poisons. Chapters include "A Is for Arrow Poison" in "The Case of the Caretaker"; "H Is for Hydrochloric Acid" in Murder in Mesopotamia; and the snake-derived "V is for Venom" as deployed in Death in the Clouds. Poison was Christie's preferred method of dispatching her victims, and her "toxic choices were perfect," according to Harkup's introduction, which details how Christie came to her in-depth knowledge by serving as a pharmaceutical dispenser during WWI and WWII. Harkup explains chemical compounds and symptoms in a way both fascinating and clear throughout, all the while writing with admiration about how inventive and accurate Christie was in picking her poisons. Readers needn't fear whodunit revelations; Harkup provides spoiler alerts. A must for chemistry buffs and Agatha Christie fans alike.

From Booklist, Copyright (c) American Library Association. Used with permission.
Review by Library Journal Review

Former chemist Harkup follows up her A Is for Arsenic with this new book. A long-time fan of Agatha Christie, Harkup focuses on 14 different poisons and how they were used as murder weapons in Christie's various stories. Readers of this book should have some interest in chemistry, as each type of poison is explored in-depth, often alongside diagrams of chemical structures, making the text quite science-heavy for the casual reader. However, Harkup's explanations are engaging, clear, and forthright, which helps the readability for those who are less science-inclined. Each chapter contains an introduction to the poison, a thorough description, instances where Christie used various versions of the chemical in her stories, how the poison kills, and a discussion of any antidotes. Along with the science, Harkup uses many examples from Christie's writings where these poisons were utilized so that fans of her works will have enough to keep them busy. There are two spoilers in the text, but they are well-marked. VERDICT Fans of Christie's novels, especially readers interested in the use of chemistry and poisons in crime fiction, will find this book worthwhile.--Holly Hebert

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